abstract：BACKGROUND:Preeclampsia (PE) is associated with oxidative stress in the maternal circulation and placenta. This study aimed to determine if inhibition of lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gives protection against oxidative stress-mediated trophoblast dysfunction. METHODS:Plasma and placen...

journal_title：Gynecologic and obstetric investigation

authors： Zhang Y,Ye Y,Wang Y,Chen W

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Low molecular weight heparin is recommended for the treatment of venous thromboembolism (VTE) during pregnancy. However, there are few reliable data regarding the safety of therapeutic doses of tinzaparin in this setting. The objective of this study was to assess the safety of once-daily therapeutic dos...

journal_title：Gynecologic and obstetric investigation

authors： Parent F,Deruelle P,Sanchez O,Meyer G,Girard P,Jilwan F,Boyer-Neumann C,Wolf M,Simonneau G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUNDS:What is not clear as yet is not only the etiology, but also the management of osseous metaplasia. We describe an infertile patient with osseous metaplasia and subsequent pregnancy after treatment and review the literature from infertility perspective. METHOD:We presented a 30-year-old woman with 8 years of...

journal_title：Gynecologic and obstetric investigation

authors： Bozdag G,Mumusoglu S,Dogan S,Esinler I,Gunalp S

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of five methods including the ThinPrep cytological test (TCT), liquid-based cytology, the human papillomavirus (HPV) test, detection of the TERC and C-MYC genes and visual inspection with acetic acid/Lugol's iodine (VIA/VILI) for opportunistic cervical cancer screening, and to ex...

journal_title：Gynecologic and obstetric investigation

authors： Gao K,Eurasian M,Zhang J,Wei Y,Zheng Q,Ye H,Li L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The transmembrane protein dystroglycan (DG) is known to anchor the cell membrane to the extracellular matrix, and is susceptible to cleavage by matrix metalloproteinases. This study tested the hypothesis that changes in DG abundance in fetal membranes (FM) occur late in gestation, with spontaneous ruptu...

journal_title：Gynecologic and obstetric investigation

authors： Theiler RN,Snyder RR,Theiler SK

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Pentraxin 3 (PTX3) is a novel vascular inflammatory marker which increases in vascular events such as diabetes mellitus. The aim of this study was to investigate the relationship between serum PTX3 levels and gestational diabetes mellitus (GDM). METHODS:This prospective observational study was comprised of ...

journal_title：Gynecologic and obstetric investigation

authors： Yildirim M,Simavli SA,Uysal Derbent A,Kaygusuz I,Uysal S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The purpose of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in sclerostin (SOST), dickkopf (DKK), secreted frizzled-related protein (sFRP) genes and bone mineral density (BMD) in postmenopausal Korean women. METHODS:The SOST, Wnt inhibitory factor 1 (WIF1...

journal_title：Gynecologic and obstetric investigation

authors： Lee DO,Kim H,Ku SY,Kim SH,Kim JG

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the influence on fertility and pregnancy outcome in cervical intraepithelial neoplasia (CIN) patients after a loop electrosurgical excision procedure (LEEP) or cold-knife conization (CKC). METHODS:269 patients with CIN-II-III who wanted to conceive were prospectively ...

journal_title：Gynecologic and obstetric investigation

authors： Liu Y,Qiu HF,Tang Y,Chen J,Lv J

更新日期：2014-01-01 00:00:00

abstract：:There is no current consensus on the best treatment modality for cesarean scar pregnancy (CSP) with favorable reproductive and pregnancy outcome. We treated 3 cases of symptomatic CSP with fetal cardiac activity. The first case underwent laparoscopic repair at 6 weeks' gestational age of unruptured CSP. The second pat...

journal_title：Gynecologic and obstetric investigation

authors： Yang G,Lee D,Lee S,Jeong K

更新日期：2014-01-01 00:00:00

abstract：:We describe a rare case of complete hydatidiform mole with twin live fetus (CHMTF) confirmed by histopathology, flow cytometry and polymerase chain reaction techniques. No malformations were observed, fetal karyotype was normal and β-human chorionic gonadotropin levels were high (>100,000 IU/ml). The patient was infor...

journal_title：Gynecologic and obstetric investigation

authors： Sánchez-Ferrer ML,Hernández-Martínez F,Machado-Linde F,Ferri B,Carbonel P,Nieto-Diaz A

更新日期：2014-01-01 00:00:00

abstract：:Gestational diabetes (GD), defined as carbohydrate intolerance with onset or first recognition during pregnancy, has a prevalence of 7% and is a growing problem worldwide. Infants born to mothers with GD are more likely to be large for gestational age, incur traumatic birth injury, require a stay in the intensive care...

journal_title：Gynecologic and obstetric investigation

authors： Correa PJ,Vargas JF,Sen S,Illanes SE

更新日期：2014-01-01 00:00:00

abstract：AIMS:To investigate misoprostol use as a self-administered medical abortifacient and to explore the knowledge and availability of misoprostol and attitudes towards it among Saudi women. METHODS:A questionnaire-based cross-sectional study was conducted in obstetric and gynecological outpatient clinics at private and te...

journal_title：Gynecologic and obstetric investigation

authors： Alsibiani SA

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:To assess the performance of colposcopists and correlate it with their experience when diagnosing cervical pathology by reviewing conventional colposcopy (CC) digital images and the Dynamic Spectral Imaging System (DySIS) cervical map. METHODS:Images from 50 women with normal and abnormal cervix collec...

journal_title：Gynecologic and obstetric investigation

authors： Coronado PJ,Fasero M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adiponectin receptor 1 (ADIPOR1) is an identified receptor for adiponectin, an adipocytokine with anti-inflammatory and insulin-sensitizing properties. The ADIPOR1 gene is a potential candidate gene in polycystic ovary syndrome (PCOS). The aim of this study is to assess the association between single-nu...

journal_title：Gynecologic and obstetric investigation

authors： Yang Z,Yang X,Xu J,Sun Y,Shi Y,Fang S

更新日期：2014-01-01 00:00:00

abstract：AIMS:To establish leukocyte count and differential percentiles in healthy singleton term laboring women during spontaneous normal vaginal labor following an uncomplicated pregnancy. METHODS:An analysis of the records of all women (n = 762) who delivered at our delivery ward during a 2-month period was performed. After...

journal_title：Gynecologic and obstetric investigation

authors： Lurie S,Weiner E,Golan A,Sadan O

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:To review the literature and compare detection rates, false negative (FN) rates, and negative predictive values (NPVs) of sentinel lymph node (SLN) biopsy in endometrial cancer to those in breast and vulvar cancer. Secondary objectives were to evaluate techniques of SLN biopsy in endometrial cancer. ME...

journal_title：Gynecologic and obstetric investigation

authors： Levinson KL,Escobar PF

更新日期：2013-01-01 00:00:00

abstract：AIMS:To estimate the prevalence of tumor spread to the parametrium, vagina and uterine corpus in radical hysterectomy specimens and define a subgroup of patients with low-risk of extracervical involvement, who may benefit from less radical surgery. METHODS:We retrospectively reviewed 96 patients with stage IA1-IIA cer...

journal_title：Gynecologic and obstetric investigation

authors： Meirovitz M,Sade S,Dreiher J,Shaco-Levy R

更新日期：2013-01-01 00:00:00

abstract：AIMS:To summarize the clinical features, perioperative management and maternal and neonatal outcomes of patients with acute fatty liver of pregnancy (AFLP) and to discuss the management of anesthesia in these patients. METHODS:This study was a retrospective review over a period of 5 years and 9 months; 28 cases from t...

journal_title：Gynecologic and obstetric investigation

authors： Zhou G,Zhang X,Ge S

更新日期：2013-01-01 00:00:00

abstract：AIM:To compare outcomes after laparoscopic ovarian cystectomy versus fenestration/coagulation or laser ablation for the treatment of endometriomas. METHODS:Studies were identified by searching the PubMed, EMBASE, SCOPUS, and Cochrane Central Register of Controlled Trials databases using the terms ovarian, endometrioma...

journal_title：Gynecologic and obstetric investigation

authors： Dan H,Limin F

更新日期：2013-01-01 00:00:00

abstract：AIMS:This study compared the effectiveness of solifenacin succinate (SS) versus percutaneous tibial nerve stimulation (PTNS) in women with overactive bladder syndrome (OABS). METHODS:A randomized controlled crossover study of 40 women with OABS was performed. Patients were randomized into two groups. In group A, patie...

journal_title：Gynecologic and obstetric investigation

authors： Vecchioli-Scaldazza C,Morosetti C,Berouz A,Giannubilo W,Ferrara V

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:The Accreditation Council for Graduate Medical Education (ACGME) requires that all Ob/Gyn residents accomplish scholarly activity. We hypothesize resident productivity is poor. METHODS:This was a web-based two-survey study using SurveyMonkey®. Surveys queried both program directors and residents regard...

journal_title：Gynecologic and obstetric investigation

authors： Oakley SH,Crisp CC,Estanol MV,Fellner AN,Kleeman SD,Pauls RN

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Previous studies on the effects of estrogen on sclerostin regulation were conducted in postmenopausal women in humans or animals following estrogen treatment or induced estrogen deficiency. The aim of this study was to evaluate the effects of sex hormones on serum sclerostin levels in premenopausal wome...

journal_title：Gynecologic and obstetric investigation

authors： Cidem M,Usta TA,Karacan I,Kucuk SH,Uludag M,Gun K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:We sought to compare the pullout strengths of the sacral end of the sacrocolpopexy mesh when attached using one suture at the first versus second sacral vertebral level (S1 vs. S2) in female cadaveric pelvises. METHODS:The sacral vertebrae were isolated in 9 unembalmed female cadavers, and segments of polyp...

journal_title：Gynecologic and obstetric investigation

authors： Shippey S,Sutter E,Belkoff SM,Gutman R,Chen CC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:To assess whether patients prefer surgery or a pessary as treatment for pelvic organ prolapse (POP). METHODS:A structured interview was performed among treated and untreated women with POP. We conducted fictive scenarios of potential disadvantages of surgery and pessary use. Our main outcome was the wi...

journal_title：Gynecologic and obstetric investigation

authors： Thys SD,Roovers JP,Geomini PM,Bongers MY

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence of glucose intolerance postpartum in women with gestational diabetes (GDM) and assess body weight, cholesterol and triglyceride concentrations after delivery. METHODS:This was a study of an initial cohort of 100 women with GDM who were tested at 6 weeks, 6 months, and 1 year post...

journal_title：Gynecologic and obstetric investigation

authors： Saucedo R,Zarate A,Basurto L,Hernandez M,Puello E,Campos S,Moreno E

更新日期：2012-01-01 00:00:00

abstract：:The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of e...

journal_title：Gynecologic and obstetric investigation

authors： Benagiano G,d'Arcangues C,Harris Requejo J,Schafer A,Say L,Merialdi M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIM:To evaluate the efficacy and tolerability of postoperative depot medroxyprogesterone acetate (DMPA) versus postoperative continuous oral contraceptive (OC) pills in the treatment of endometriosis-associated pain. METHODS:After a conservative surgery, 84 patients with symptomatic endometriosis were rando...

journal_title：Gynecologic and obstetric investigation

authors： Cheewadhanaraks S,Choksuchat C,Dhanaworavibul K,Liabsuetrakul T

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adenomyosis is a common condition with a poorly understood pathogenesis. Recent data suggest that it may be an epigenetic disease. This study investigated the expression and localization of class I histone deacetylases (HDACs) in women with and without adenomyosis. METHODS:The ectopic and homologous eu...

journal_title：Gynecologic and obstetric investigation

authors： Liu X,Nie J,Guo SW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:The purpose of this study was to determine the relationship between maternal characteristics and severe postpartum hemorrhage (PPH). METHODS:Medical records of women who delivered at Duke University Hospital between 2001 and 2004 with an ICD-9 code for PPH were reviewed. Women with PPH who received blo...

journal_title：Gynecologic and obstetric investigation

authors： Paglia MJ,Grotegut CA,Johnson LN,Thames B,James AH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:To test the hypothesis that obstetrical disseminated intravascular coagulopathy results from an excessive leakage of fetal material into the maternal circulation. METHODS:All peripartum hysterectomy cases for hemorrhage at two suburban Illinois hospitals over 10 years were included. Intravascular prese...

journal_title：Gynecologic and obstetric investigation

authors： Benson MD,Cheema N,Kaufman MW,Goldschmidt RA,Beaumont JL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:To determine the clinicopathological characteristics and potentially associated outcomes in patients diagnosed with serous adenocarcinoma of the uterine cervix. METHODS:The records of surgically-treated patients with pathological stage pT1b-2b serous adenocarcinoma were reviewed. RESULTS:Of 12 patient...

journal_title：Gynecologic and obstetric investigation

authors： Togami S,Kasamatsu T,Sasajima Y,Onda T,Ishikawa M,Ikeda S,Kato T,Tsuda H

更新日期：2012-01-01 00:00:00

abstract：AIMS:To compare a surgical-margin thermal artifact in 3 techniques of loop excision of the transformation zone (LETZ). METHODS:The histopathologic specimens from 140 patients who underwent 3 techniques of LETZ with different electrosurgical units (large loop used with a Valleylab, large loop used with an Ellman Surgit...

journal_title：Gynecologic and obstetric investigation

authors： Boonlikit S,Yanaranop M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIM:Marginal or decreased amniotic fluid volume by ultrasound estimate and fetal growth restriction have been shown to be significantly associated with perinatal mortality. The association of fetal growth restriction and precisely measured amniotic fluid volume is unknown. The purpose of this study was to de...

journal_title：Gynecologic and obstetric investigation

authors： Magann EF,Haas DM,Hill JB,Chauhan SP,Watson EM,Learman LA

更新日期：2011-01-01 00:00:00

abstract：AIM:To compare the effect of suprapubic and transurethral catheterization on postvoid residual volumes (PRVs) after cystocele repair. METHODS:126 women who underwent pelvic organ prolapse surgery including cystocele repair were randomized to suprapubic or transurethral catheterization. At the third postoperative day, ...

journal_title：Gynecologic and obstetric investigation

authors： Stekkinger E,van der Linden PJ

更新日期：2011-01-01 00:00:00

abstract：:Minimal deviation adenocarcinoma (MDA) is a very rare variant of cervical adenocarcinoma, this pathological entity is composed of mucinous very-well-differentiated glands deeply invading cervical stroma, and often surrounded by a desmoplastic reaction. Despite its benign histological appearance, MDA is typically chara...

journal_title：Gynecologic and obstetric investigation

authors： Ferrandina G,Carbone A,Macchia G,Petrillo M,Lucidi A,Morganti AG

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:To compare the vaginal route and laparoscopic suture for vaginal cuff closure (VCC) in patients undergoing a total laparoscopic hysterectomy (TLH). METHODS:A total of 471 women who required hysterectomy were allocated to two groups. 261 women had TLH via VCC by the vaginal route and 210 women had TLH via VC...

journal_title：Gynecologic and obstetric investigation

authors： Hwang JH,Lee JK,Lee NW,Lee KW

更新日期：2011-01-01 00:00:00

abstract：AIM:To evaluate the value of serum fructosamine as a screening test for gestational diabetes mellitus (GDM). METHODS:849 pregnant women underwent the one-step 75 g oral glucose tolerance test (OGTT) for universal screening of GDM. The fasting serum fructosamine (cFruc) was assessed using the area under the receiver op...

journal_title：Gynecologic and obstetric investigation

authors： Agarwal MM,Dhatt GS,Othman Y,Ljubisavljevic MR

更新日期：2011-01-01 00:00:00

abstract：AIM:The aim of this study was to assess various treatment options in stage IB2 cervical cancer patients. METHODS:Between January 1995 and May 2007, 63 patients with stage IB2 were treated by radical hysterectomy (n = 28), primary concurrent chemoradiation (CCRT, n = 16) or radiation therapy (RT, n = 19). Disease-free ...

journal_title：Gynecologic and obstetric investigation

authors： Kim WY,Chang SJ,Chang KH,Yoo SC,Chun M,Ryu HS

更新日期：2011-01-01 00:00:00

abstract：AIMS:To investigate the differences in insulin resistance between women with recurrent miscarriage and those with normal pregnancy. METHODS:Pregnant women with a history of recurrent miscarriage were included in the patient group (n = 97), while those with no history of abnormal pregnancy were included in the control ...

journal_title：Gynecologic and obstetric investigation

authors： Wang Y,Zhao H,Li Y,Zhang J,Tan J,Liu Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Perinatal environmental exposure may affect fetal development and reprogram the developing organism for adult-onset disease. In this case-control study, we aimed at assessing this pathogenetic model in endometriosis. METHODS:Consecutive patients with a first laparoscopic diagnosis of endometriosis were...

journal_title：Gynecologic and obstetric investigation

authors： Somigliana E,Vigano P,Abbiati A,Paffoni A,Benaglia L,Vercellini P,Fedele L

更新日期：2011-01-01 00:00:00